SCHEMBL8992846

SCHEMBL8992846

OCCN(CCO)c1ccc(N=Nc2cccnc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.43
KMT2A Q03164 8/20 0.43
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
MITF O75030 2/20 0.43
PSMD14 O00487 1/20 0.43
HTR3E A5X5Y0 1/20 0.40
HTR3B O95264 1/20 0.40
HTR3A P46098 1/20 0.40
HTR3D Q70Z44 1/20 0.40
HTR3C Q8WXA8 1/20 0.40
MEN1 O00255 7/20 0.37
NOS3 P29474 2/20 0.36
NOS1 P29475 2/20 0.36
NOS2 P35228 2/20 0.36
NPSR1 Q6W5P4 3/20 0.35
GFER P55789 1/20 0.35
ALDH1A1 P00352 5/20 0.35
TDP1 Q9NUW8 5/20 0.35
MAPK1 P28482 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1131912 0.82 KMT2A (0.48) MAPTKMT2ANPC1RAB9AMITF
SCHEMBL1131911 0.82 KMT2A (0.48) MAPTKMT2ANPC1RAB9AMITF
SCHEMBL1615340 0.82 ALDH1A1 (0.52) MAPTKMT2ANPC1RAB9AMITF
SCHEMBL9644455 0.82 ALDH1A1 (0.52) MAPTKMT2ANPC1RAB9AMITF
SCHEMBL8992872 0.76 MAPT (0.43) MAPTKMT2ANPC1RAB9AMITF
SCHEMBL3161554 0.76 MAPK1 (0.63) MAPTKMT2ANPC1RAB9AHTR3E
SCHEMBL13686031 0.76 MAPK1 (0.63) MAPTKMT2ANPC1RAB9AHTR3E
SCHEMBL19831101 0.75 NPC1 (0.47) MAPTKMT2ANPC1RAB9AMITF
SCHEMBL14366671 0.75 MAOA (0.61) MAPTKMT2ANPC1RAB9AMITF
Hydrochloric Acid SCHEMBL8745041 0.74 MAPK1 (0.61) MAPTKMT2ANPC1RAB9AHTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970685-B2 Composition for dyeing keratinous fibres containing a cationic direct dye and a thickening polymer ORÉAL L (FR) 2016-10-19 EP disclosed
EP-0601302-B1 Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes WELLA AG (DE) 1996-07-10 EP disclosed
EP-0601302-A1 Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes Wella Aktiengesellschaft (DE) 1994-06-15 EP disclosed