Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CASR | P41180 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291146 | 0.84 | MGLL (0.50) | TSHRALDH1A1L3MBTL1RAB9AMAPT | |
| SCHEMBL1765701 | 0.80 | SLC6A2 (0.51) | TSHRALDH1A1RAB9AMAPTCYP2C9 | |
| SCHEMBL14967041 | 0.80 | CYP3A4 (0.53) | TSHRALDH1A1GAAMAPTCYP1A2 | |
| SCHEMBL14661699 | 0.80 | SLC6A2 (0.51) | TSHRALDH1A1RAB9AMAPTCYP2C9 | |
| SCHEMBL14670208 | 0.80 | CYP3A4 (0.53) | TSHRALDH1A1GAAMAPTCYP1A2 | |
| SCHEMBL11901631 | 0.80 | SLC6A2 (0.51) | TSHRALDH1A1RAB9AMAPTCYP2C9 | |
| SCHEMBL10610472 | 0.80 | SLC6A2 (0.51) | TSHRALDH1A1RAB9AMAPTCYP2C9 | |
| SCHEMBL2680771 | 0.80 | TSHR (0.64) | TSHRALDH1A1L3MBTL1GAARAB9A | |
| SCHEMBL866718 | 0.80 | TSHR (0.64) | TSHRALDH1A1L3MBTL1GAARAB9A | |
| SCHEMBL30251598 | 0.80 | TSHR (0.64) | TSHRALDH1A1L3MBTL1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |