Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIF5B | P33176 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ETV6 | P41212 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993192 | 0.93 | FYN (0.41) | MAPTFYNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8992897 | 0.90 | FYN (0.41) | MAPTFYNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8993240 | 0.87 | MAPT (0.41) | MAPTFYNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8993183 | 0.86 | FYN (0.40) | MAPTFYNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8993293 | 0.85 | KMT2A (0.40) | MAPTFYNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8992845 | 0.84 | FYN (0.40) | MAPTFYNMEN1KMT2AKIT | |
| SCHEMBL8992831 | 0.83 | LTA4H (0.42) | MAPTFYNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8993290 | 0.83 | GPR119 (0.41) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8993124 | 0.82 | GPR119 (0.37) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9218703 | 0.81 | MAPT (0.48) | MAPTFYNNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |