Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19194110 | 0.81 | KDM4E (0.45) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14967251 | 0.81 | KDM4E (0.45) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14972261 | 0.81 | KDM4E (0.45) | CA12CA1CA2CA9CA14 | |
| SCHEMBL30251598 | 0.80 | TSHR (0.64) | PPARASRD5A2CA12CA1CA2 | |
| SCHEMBL866718 | 0.80 | TSHR (0.64) | PPARASRD5A2CA12CA1CA2 | |
| SCHEMBL12487853 | 0.79 | TRPA1 (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL10632616 | 0.79 | CA12 (0.47) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14967139 | 0.78 | TSHR (0.48) | PPARATSHRKMT2AALDH1A1GAA | |
| SCHEMBL19194090 | 0.78 | TSHR (0.48) | PPARATSHRKMT2AALDH1A1GAA | |
| SCHEMBL14972264 | 0.78 | TSHR (0.48) | PPARATSHRKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |