Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50385 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL11767985 | 0.89 | IDO1 (0.50) | IDO1MEN1KMT2ATSHRTAAR1 | |
| SCHEMBL8995754 | 0.89 | IDO1 (0.50) | IDO1MEN1KMT2ATSHRTAAR1 | |
| SCHEMBL260498 | 0.86 | TSHR (0.56) | KMT2ATSHRESR1ESR2HDAC8 | |
| SCHEMBL1106684 | 0.86 | IDO1 (0.58) | IDO1MEN1KMT2AMAPTTSHR | |
| SCHEMBL11318432 | 0.86 | TSHR (0.56) | KMT2ATSHRESR1ESR2HDAC8 | |
| Alcohol SCHEMBL20495951 | 0.84 | IDO1 (0.46) | IDO1MEN1KMT2ATSHRTAAR1 | |
| SCHEMBL3994114 | 0.84 | MAOB (0.52) | IDO1MEN1KMT2ATSHRTAAR1 | |
| Cyclopropane SCHEMBL5862696 | 0.84 | ALDH1A1 (0.52) | IDO1MEN1KMT2ATSHRTAAR1 | |
| SCHEMBL16663705 | 0.84 | TAAR1 (0.54) | IDO1TSHRESR1ESR2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |