Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.78 |
| ▸ | CA2 | P00918 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.62 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.62 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16573858 | 0.93 | CA1 (0.68) | CA1CA2MAPTKMT2AMEN1 | |
| SCHEMBL69454 | 0.90 | LOXL2 (0.70) | CA1CA2MAPTKMT2AMEN1 | |
| SCHEMBL9234845 | 0.89 | CA1 (0.60) | CA1CA2MAPTKMT2AMEN1 | |
| SCHEMBL12294447 | 0.89 | CA1 (0.78) | CA1CA2MAPTKMT2AMEN1 | |
| SCHEMBL28266082 | 0.89 | CA1 (0.78) | CA1CA2MAPTKMT2AMEN1 | |
| Methyl 4-Methoxybenzoate SCHEMBL231243 | 0.88 | CA1 (1.00) | CA1CA2MAPTKMT2AMEN1 | |
| SCHEMBL1897614 | 0.87 | CA1 (0.59) | CA1CA2MAPTKMT2AMEN1 | |
| Methyl 4-Methoxybenzoate SCHEMBL27405603 | 0.86 | CA1 (0.95) | CA1CA2MAPTKMT2AMEN1 | |
| SCHEMBL28232519 | 0.85 | RAB9A (0.63) | CA1CA2MAPTKMT2AMEN1 | |
| SCHEMBL14157088 | 0.84 | CA1 (0.70) | CA1CA2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111548269-A | Preparation method of diarylmethane structure compound | 兰州大学 | 2020-08-18 | — | — | CN | disclosed |
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |