Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193931 | 0.77 | CYP2D6 (0.48) | KMT2ATSHRMAPTLMNAKDM4E | |
| SCHEMBL10585427 | 0.77 | TSHR (0.45) | KMT2AL3MBTL1MEN1NPC1TRPA1 | |
| SCHEMBL10567235 | 0.77 | TRPA1 (0.45) | KMT2AMEN1NPC1PKMTRPA1 | |
| SCHEMBL8992978 | 0.77 | MAOB (0.42) | KMT2AL3MBTL1MEN1NPC1TRPA1 | |
| SCHEMBL5084681 | 0.77 | TSHR (0.48) | KMT2AL3MBTL1PKMTSHRMAPT | |
| SCHEMBL11449880 | 0.75 | ESR1 (0.37) | KMT2AL3MBTL1MEN1NPC1PKM | |
| Acetaldehyde SCHEMBL1720078 | 0.74 | KMT2A (0.43) | KMT2AL3MBTL1MEN1NPC1THRB | |
| SCHEMBL8993022 | 0.72 | HTR2A (0.41) | KMT2APBRM1LMNAMAOBCYP2D6 | |
| SCHEMBL10564457 | 0.72 | MAOB (0.42) | KMT2AMEN1NPC1TRPA1PBRM1 | |
| SCHEMBL7042455 | 0.72 | EPHX1 (0.49) | KMT2AL3MBTL1MEN1HTTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |