Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993225 | 0.85 | IDH1 (0.47) | CNR2GPR55CNR1DHFRCHRM2 | |
| SCHEMBL5646180 | 0.84 | ANO1 (0.50) | CNR2GPR55CNR1DHFRCHRM2 | |
| SCHEMBL5648684 | 0.83 | CNR2 (0.52) | CNR2GPR55CNR1DHFRCHRM2 | |
| SCHEMBL29484318 | 0.82 | TAAR1 (0.60) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL228859 | 0.82 | TAAR1 (0.60) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL8992807 | 0.82 | CNR2 (0.46) | CNR2GPR55CNR1DHFRCHRM2 | |
| SCHEMBL8992935 | 0.81 | TAAR1 (0.41) | CNR2CNR1TAAR1IDO1MAPT | |
| SCHEMBL8992966 | 0.81 | LTA4H (0.53) | CHRM2CHRM1CHRM3MTNR1AMTNR1B | |
| SCHEMBL227515 | 0.81 | TAAR1 (0.58) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL8365761 | 0.79 | LMNA (0.56) | CHRM2CHRM1CHRM3TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |