SCHEMBL8993210

SCHEMBL8993210

CCOc1ccc(-c2ccc(OCc3ccccc3)c(F)c2)cc1F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.56
FFAR1 O14842 4/20 0.52
PPARD Q03181 4/20 0.52
HTR1A P08908 2/20 0.50
ADRA1D P25100 2/20 0.50
ADRA1A P35348 2/20 0.50
ADRA1B P35368 2/20 0.50
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.47
MRGPRX4 Q96LA9 2/20 0.47
AOC3 Q16853 1/20 0.47
CTSA P10619 1/20 0.47
KDM1A O60341 2/20 0.46
S1PR5 Q9H228 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAPT P10636 1/20 0.45
MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10093047 0.86 ERN1 (0.55) ERN1FFAR1PPARDMRGPRX4CTSA
SCHEMBL10435369 0.85 ERN1 (0.52) ERN1FFAR1PPARDHTR1AMEN1
SCHEMBL8993289 0.85 ERN1 (0.57) ERN1FFAR1PPARDMRGPRX4CTSA
SCHEMBL9484876 0.85 L3MBTL1 (0.53) FFAR1PPARDKDM4EMEN1KMT2A
SCHEMBL5683106 0.84 HTR1A (0.47) ERN1FFAR1PPARDHTR1AADRA1D
SCHEMBL8619252 0.84 ERN1 (0.53) ERN1FFAR1PPARDCTSAKDM1A
SCHEMBL8617145 0.84 ERN1 (0.53) ERN1FFAR1PPARDCTSAKDM1A
SCHEMBL21162496 0.84 ERN1 (0.59) ERN1FFAR1PPARDKDM4ELMNA
SCHEMBL1128493 0.84 FFAR1 (0.59) FFAR1PPARDHTR1AADRA1DADRA1A
SCHEMBL8773970 0.84 ERN1 (0.51) ERN1FFAR1PPARDHTR1AADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545747-A STABLE FERROELECTRIC LIQUID CRYSTALLINE COMPOUNDS KANTO KAGAKU KABUSHIKI KAISHA (JP) 1996-08-13 US disclosed
EP-0496896-A1 CYCLOBUTANECARBOXYLIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME KANTO KAGAKU KABUSHIKI KAISHA (JP) 1992-08-05 EP disclosed