SCHEMBL8993234

SCHEMBL8993234

CCCCC(O)CCCOc1ccc(-c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.59
PPARA Q07869 3/20 0.59
ALOX5 P09917 2/20 0.59
PTGES O14684 1/20 0.59
LTA4H P09960 2/20 0.53
CHRNB2 P17787 1/20 0.53
CHRNB4 P30926 1/20 0.53
CHRNA3 P32297 1/20 0.53
CHRNA7 P36544 1/20 0.53
CHRNA4 P43681 1/20 0.53
LSS P48449 1/20 0.51
CYP2D6 P10635 4/20 0.51
CYP3A4 P08684 3/20 0.51
CYP19A1 P11511 3/20 0.51
CYP2C9 P11712 3/20 0.51
CYP2C19 P33261 3/20 0.51
RARB P10826 4/20 0.50
CYP1A2 P05177 2/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18166767 0.87 RARB (0.56) PPARGPPARAALOX5PTGESLTA4H
SCHEMBL9158869 0.85 LTA4H (0.70) PPARGPPARAALOX5PTGESLTA4H
SCHEMBL5551477 0.85 LTA4H (0.70) PPARGPPARAALOX5PTGESLTA4H
SCHEMBL6302467 0.84 ALOX5 (0.59) PPARGPPARAALOX5PTGESLTA4H
Biphenyl SCHEMBL28775815 0.84 PPARA (0.50) PPARGPPARAALOX5PTGESPPARD
Biphenyl SCHEMBL28775812 0.84 PPARA (0.50) PPARGPPARAALOX5PTGESPPARD
SCHEMBL15178102 0.83 TDP1 (0.55) PPARGPPARAALOX5LTA4HCHRNB2
SCHEMBL27745892 0.82 MAPT (0.55) PPARGPPARAALOX5PTGESCHRNA7
SCHEMBL6024662 0.82 ALOX5 (0.53) PPARGPPARAALOX5PTGESLTA4H
SCHEMBL1032924 0.81 LTA4H (0.72) LTA4HCHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545747-A STABLE FERROELECTRIC LIQUID CRYSTALLINE COMPOUNDS KANTO KAGAKU KABUSHIKI KAISHA (JP) 1996-08-13 US disclosed
US-5137653-A Alkanoyl ester compounds and their intermediates and method of producing the same NIPPON MINING CO., LTD. (JP) 1992-08-11 US disclosed
EP-0311692-B1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1992-07-08 EP disclosed
EP-0311692-A1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1989-04-19 EP disclosed