Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 3/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992916 | 0.87 | DHFR (0.46) | KDM4CTACR1DHFR | |
| SCHEMBL27316374 | 0.83 | KDM4C (0.39) | KDM4CCREBBPEP300TACR1DHFR | |
| SCHEMBL4184332 | 0.80 | KDM4C (0.47) | KDM4CCREBBPEP300TACR1ICAM1 | |
| SCHEMBL18355699 | 0.79 | TACR1 (0.46) | KDM4CCREBBPEP300TACR1MEN1 | |
| SCHEMBL11258174 | 0.79 | KDM4C (0.46) | KDM4CCREBBPEP300TACR1ICAM1 | |
| SCHEMBL8992945 | 0.79 | ICAM1 (0.38) | KDM4CCREBBPEP300TACR1ICAM1 | |
| SCHEMBL92906 | 0.79 | DRD4 (0.47) | KDM4CCREBBPEP300TACR1ICAM1 | |
| SCHEMBL14650403 | 0.78 | ICAM1 (0.36) | KDM4CCREBBPEP300DHFRICAM1 | |
| SCHEMBL8992804 | 0.78 | DHFR (0.39) | CREBBPTACR1DHFRICAM1SELE | |
| SCHEMBL14650399 | 0.78 | CREBBP (0.34) | KDM4CCREBBPEP300DHFRICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036919-C | Pyrazole condensed ring derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMA CO LTD (JP) | 1998-01-07 | — | — | CN | disclosed |
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| CN-1089609-A | Pyrazole-fused ring derivatives, its manufacture method and male hormone inhibitor | OTSUKA PHARMA CO LTD (JP) | 1994-07-20 | — | — | CN | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |