SCHEMBL8993267

SCHEMBL8993267

O=C(ON1CCCCC1)c1cccc(O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
MAPT P10636 1/20 0.53
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA6 P23280 1/20 0.46
CA9 Q16790 1/20 0.46
PARP1 P09874 1/20 0.44
RAB9A P51151 4/20 0.42
NPC1 O15118 4/20 0.42
SLC2A1 P11166 1/20 0.42
SLC2A4 P14672 1/20 0.42
KDM4E B2RXH2 2/20 0.42
EGLN2 Q96KS0 1/20 0.42
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TP53 P04637 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5893722 0.84 NPC1 (0.46) ALDH1A1MAPTCA12CA1CA2
SCHEMBL15571508 0.83 GAA (0.51) ALDH1A1MAPTCA12CA1CA2
SCHEMBL15571345 0.83 ALDH1A1 (0.51) ALDH1A1MAPTCA12CA1CA2
SCHEMBL15572098 0.83 GAA (0.51) ALDH1A1MAPTCA12CA1CA2
SCHEMBL15571800 0.83 GAA (0.51) ALDH1A1MAPTCA12CA1CA2
SCHEMBL1249246 0.81 HPGD (0.53) ALDH1A1MAPTRAB9ANPC1MEN1
SCHEMBL28495717 0.81 HPGD (0.53) ALDH1A1MAPTRAB9ANPC1MEN1
SCHEMBL27446747 0.81 RAB9A (0.48) ALDH1A1RAB9ANPC1KDM4EKMT2A
SCHEMBL8992905 0.80 KMT2A (0.55) ALDH1A1MAPTCA12CA1CA2
SCHEMBL29098438 0.80 HPGD (0.52) ALDH1A1MAPTRAB9ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0526486-B1 NON-LINEAR OPTICAL DEVICE SECR DEFENCE BRIT (GB) 1996-07-31 EP disclosed
US-5352388-A Crystalline second harmonic generator material comprising salt of organic nitrogenous base and optically active enantiomer of chiral carboxylic acid mounted in optical path of laser THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDON OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1994-10-04 US disclosed