Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NHERF1 | O14745 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29293878 | 0.72 | KDM4E (0.63) | KDM4ERAB9AHSD17B10ALDH1A1MEN1 | |
| SCHEMBL7835189 | 0.66 | KDM4E (0.49) | KDM4ERAB9ANPC1DHODHALDH1A1 | |
| SCHEMBL29293884 | 0.66 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1MEN1LMNA | |
| SCHEMBL5594687 | 0.66 | KDM4E (0.68) | KDM4ERAB9ANPC1GRIK1DHODH | |
| SCHEMBL3629659 | 0.65 | KMT2A (0.57) | KDM4ERAB9ANPC1DHODHALDH1A1 | |
| SCHEMBL1157612 | 0.65 | EPHX2 (0.57) | KDM4EHSD17B10KMT2ASERPINE1GAA | |
| SCHEMBL11603203 | 0.64 | FABP4 (0.69) | KDM4EGRIK1HSD17B10DHODHALDH1A1 | |
| SCHEMBL11637217 | 0.64 | MAPT (0.57) | ALDH1A1MEN1LMNAKMT2AGAA | |
| SCHEMBL29293876 | 0.63 | HPGD (0.54) | KDM4ERAB9ANPC1HSD17B10ALDH1A1 | |
| SCHEMBL4912839 | 0.63 | TSHR (0.66) | KDM4EDHODHALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | claimed |