Aminobenzoic Acid

Aminobenzoic Acid

SCHEMBL8993340

Nc1ccc(C(=O)O)cc1.O=C(O)CCCC1c2ccccc2-c2ccccc21

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.46
KMT2A Q03164 2/20 0.44
GRM5 P41594 1/20 0.40
GRM1 Q13255 1/20 0.40
HTR2A P28223 1/20 0.38
HDAC3 O15379 2/20 0.37
HDAC4 P56524 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC7 Q8WUI4 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC10 Q969S8 2/20 0.37
HDAC11 Q96DB2 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
HDAC9 Q9UKV0 2/20 0.37
HDAC5 Q9UQL6 2/20 0.37
IDO1 P14902 1/20 0.37
TOP1 P11387 1/20 0.36
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8993220 0.85 EGFR (0.58) EGFRKMT2AHTR2AHDAC3HDAC4
SCHEMBL28062991 0.80 KMT2A (0.57) EGFRKMT2AHTR2AHDAC3HDAC4
SCHEMBL3136529 0.77 EGFR (0.54) EGFRKMT2AHTR2AHDAC3HDAC4
Hydrochloric Acid SCHEMBL8993456 0.75 EGFR (0.53) EGFRKMT2AHTR2AHDAC3HDAC4
SCHEMBL14879254 0.75 PPARA (0.50) GRM5GRM1HDAC1TSHRALDH1A1
SCHEMBL17500281 0.74 RXRA (0.49) HTR2ATSHRALDH1A1PKMRXRA
Glutarate SCHEMBL3623154 0.72 KMT2A (0.52) EGFRKMT2AHTR2AHDAC3HDAC4
Aminobenzoic Acid SCHEMBL28215855 0.71 TSHR (0.62) KMT2ATSHRALDH1A1SMN1; SMN2MAPT
Aminobenzoic Acid SCHEMBL5058591 0.71 TSHR (0.70) KMT2ATSHRALDH1A1SMN1; SMN2MAPT
Aminobenzoic Acid SCHEMBL29006318 0.71 TSHR (0.67) KMT2ATSHRALDH1A1PKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5519043-A ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE SCIOS NOVA INC. (US) 1996-05-21 US claimed
US-5519043-A ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE SCIOS NOVA INC. (US) 1996-05-21 US disclosed