Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548206 | 0.91 | THRB (0.49) | THRBALDH1A1LMNATSHRHPGD | |
| SCHEMBL8550438 | 0.75 | TP53 (0.49) | THRBALDH1A1LMNATSHRHPGD | |
| SCHEMBL8547550 | 0.74 | TP53 (0.64) | THRBALDH1A1LMNATSHRHPGD | |
| SCHEMBL9854446 | 0.73 | THRB (0.54) | THRBALDH1A1TSHRHPGDHDAC3 | |
| SCHEMBL600753 | 0.70 | THRB (0.51) | THRBGAAALDH1A1LMNATSHR | |
| SCHEMBL19865605 | 0.70 | ALDH1A1 (0.38) | GAAALDH1A1LMNAHPGDHDAC3 | |
| SCHEMBL9174872 | 0.69 | THRB (0.57) | THRBALDH1A1LMNATSHRHPGD | |
| SCHEMBL8982453 | 0.68 | TSHR (0.50) | THRBGAAALDH1A1TSHRHPGD | |
| SCHEMBL17522081 | 0.68 | TSHR (0.50) | THRBALDH1A1TSHRHPGDTP53 | |
| SCHEMBL17211582 | 0.68 | TSHR (0.50) | THRBALDH1A1LMNATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724503-A1 | ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011774-A1 | ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-05-04 | — | — | WO | disclosed |