Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8993280 | 0.99 | KMT2A (0.50) | KMT2APKMPTPN12GPR35PTPN22 | |
| SCHEMBL13593266 | 0.80 | KMT2A (0.61) | KMT2APKMPTPN12GPR35PTPN22 | |
| SCHEMBL3208722 | 0.80 | EPHX2 (0.67) | KMT2APKMMEN1ALDH1A1KDM4E | |
| SCHEMBL8993427 | 0.78 | HCAR2 (0.52) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL1993952 | 0.77 | GAA (0.66) | KMT2APKMALDH1A1NPC1MAPT | |
| SCHEMBL2128835 | 0.74 | ALDH1A1 (0.68) | KMT2APKMMEN1ALDH1A1KDM4E | |
| SCHEMBL2004145 | 0.74 | TRPV1 (0.66) | KMT2APKMMEN1ALDH1A1NPC1 | |
| SCHEMBL1130032 | 0.73 | KMT2A (0.61) | KMT2APKMMEN1ALDH1A1KDM4E | |
| SCHEMBL2002326 | 0.72 | CA12 (0.64) | KMT2APKMMEN1ALDH1A1KDM4E | |
| SCHEMBL16221621 | 0.72 | KMT2A (0.59) | KMT2APKMMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472973-A | Non-steroidal antiinflammatory agents | SCIOS NOVA INC. (US) | 1995-12-05 | — | — | US | claimed |
| WO-1993011764-A1 | FLUORENYL DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCIOS NOVA INC. (US) | 1993-06-24 | — | — | WO | claimed |
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | disclosed |
| US-5472973-A | Non-steroidal antiinflammatory agents | SCIOS NOVA INC. (US) | 1995-12-05 | — | — | US | disclosed |
| WO-1993011764-A1 | FLUORENYL DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCIOS NOVA INC. (US) | 1993-06-24 | — | — | WO | disclosed |