Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404495 | 0.80 | KMT2A (0.69) | HCAR2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8993362 | 0.78 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| Water SCHEMBL8993280 | 0.77 | KMT2A (0.50) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL119223 | 0.77 | EPHX2 (0.60) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL29401765 | 0.77 | EPHX2 (0.60) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL29913938 | 0.77 | EPHX2 (0.60) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL7824993 | 0.76 | KMT2A (0.63) | HCAR2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10501327 | 0.75 | KMT2A (0.83) | HCAR2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2968441 | 0.74 | KMT2A (0.66) | HCAR2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL5622296 | 0.74 | KDM4C (0.54) | HCAR2KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472973-A | Non-steroidal antiinflammatory agents | SCIOS NOVA INC. (US) | 1995-12-05 | — | — | US | claimed |
| WO-1993011764-A1 | FLUORENYL DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCIOS NOVA INC. (US) | 1993-06-24 | — | — | WO | claimed |
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | disclosed |
| US-5472973-A | Non-steroidal antiinflammatory agents | SCIOS NOVA INC. (US) | 1995-12-05 | — | — | US | disclosed |
| WO-1993011764-A1 | FLUORENYL DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCIOS NOVA INC. (US) | 1993-06-24 | — | — | WO | disclosed |