Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.83 |
| ▸ | MAOB | P27338 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | F13A1 | P00488 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598685 | 0.91 | MAOA (1.00) | MAOAMAOBMEN1KMT2ARAB9A | |
| SCHEMBL5443582 | 0.90 | MAOA (0.69) | MAOAMAOBMEN1KMT2ACA12 | |
| SCHEMBL11055930 | 0.89 | CNR1 (0.70) | MAOAMAOBMEN1KMT2ACA12 | |
| SCHEMBL4548119 | 0.89 | CNR1 (0.70) | MAOAMAOBMEN1KMT2ACA12 | |
| SCHEMBL4555020 | 0.89 | MAPT (0.72) | MAOAMAOBMEN1KMT2ACA12 | |
| SCHEMBL3596178 | 0.86 | ALDH1A1 (0.64) | MAOAMAOBMEN1KMT2ACA12 | |
| SCHEMBL7516833 | 0.86 | MAOA (0.64) | MAOAMAOBMEN1KMT2ACA12 | |
| SCHEMBL31325109 | 0.86 | MAOA (0.64) | MAOAMAOBMEN1KMT2ACA12 | |
| SCHEMBL28609606 | 0.85 | MAOA (0.63) | MAOAMAOBMEN1KMT2ACA12 | |
| SCHEMBL4921279 | 0.85 | NPC1 (0.70) | MAOAMAOBMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684599-A | Preparation method of N, N-diaryl urea compound | 上海应用技术大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-114213286-B | Synthetic method of urea derivative | 湖北文理学院 | 2022-12-30 | — | — | CN | disclosed |
| WO-2017214505-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2017-12-14 | — | — | WO | disclosed |
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5399708-A | Cholecystokinin and gastrin antagonists; gastrointestinal and central nervous system disorders | ELI LILLY AND COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-4444863-A | UREA COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |
| US-4275215-A | QUATERNARY AMMONIUM OR PHOSPHONIUM SALTS CATALYZE REACTION OF HYPOHALITE AND A DIPHENYL UREA | DOW CHEMICAL COMPANY LIMITED (GB) | 1981-06-23 | — | — | US | disclosed |