SCHEMBL8993480

SCHEMBL8993480

C[Si](C)(C)c1cc2cc3c([Si](C)(C)C)cc3cc12

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4586058 0.76 IDO1 (0.30) IDO1
SCHEMBL4867772 0.73
SCHEMBL4586844 0.73
SCHEMBL5010702 0.71 ALDH1A1 (0.36) IDO1
SCHEMBL13408677 0.69 ALDH1A1 (0.36) IDO1
SCHEMBL4572706 0.68 IDO1 (0.32) IDO1
SCHEMBL14600079 0.68 ALDH1A1 (0.41) IDO1
SCHEMBL18088199 0.68 CYP1A2 (0.41) IDO1
SCHEMBL15945795 0.67 IDO1 (0.34) IDO1
SCHEMBL5011009 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5552508-A Difunctional bitricyclodecatriene monomers UNIVERSITY OF MICHIGAN, THE BOARD OF REGENTS (US) 1996-09-03 US disclosed