SCHEMBL5010702

SCHEMBL5010702

C[Si](C)(C)c1cc2ccc3cc([Si](C)(C)C)c([Si](C)(C)C)cc3c2cc1[Si](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HIF1A Q16665 1/20 0.36
CYP1B1 Q16678 1/20 0.36
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4586058 0.78 IDO1 (0.30) IDO1
SCHEMBL4867772 0.76
SCHEMBL4586844 0.76
SCHEMBL5011009 0.75
SCHEMBL28862736 0.72 GPR3 (0.36) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL4572706 0.71 IDO1 (0.32) IDO1
SCHEMBL8993480 0.71 IDO1 (0.35) IDO1
SCHEMBL12269047 0.67 ALDH1A1 (0.42) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL11354700 0.66 CYP1A2 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL15843580 0.66 MCL1 (0.56) ALDH1A1HSD17B10HIF1ACYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207864-A1 Organosilanes, Process For Production of the Same, and Use Thereof SHARP KABUSHIKI KAISHA (JP) 2008-08-28 US disclosed