Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.57 |
| ▸ | MMP13 | P45452 | 3/20 | 0.57 |
| ▸ | MMP2 | P08253 | 3/20 | 0.57 |
| ▸ | MMP8 | P22894 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.55 |
| ▸ | STAT3 | P40763 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA3 | P07451 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993667 | 0.86 | APP (0.48) | MMP9MMP2ALOX5NFKB1APP | |
| Ferulate SCHEMBL5907599 | 0.76 | KDM4E (0.67) | MMP9MMP13MMP2MMP8CYP2D6 | |
| SCHEMBL12088589 | 0.76 | MMP9 (0.72) | MMP9MMP13MMP2MMP8CYP2D6 | |
| SCHEMBL5598941 | 0.76 | APP (0.73) | MMP9MMP13MMP2MMP8CYP2D6 | |
| SCHEMBL5598945 | 0.76 | APP (0.73) | MMP9MMP13MMP2MMP8CYP2D6 | |
| SCHEMBL4421260 | 0.76 | APP (0.72) | MMP9MMP13MMP2MMP8CYP2D6 | |
| SCHEMBL21858153 | 0.76 | APP (0.72) | MMP9MMP13MMP2MMP8CYP2D6 | |
| SCHEMBL8993581 | 0.76 | PPARG (0.68) | CYP2D6CA12CA4CA6CA5A | |
| SCHEMBL8993585 | 0.76 | PPARG (0.68) | CYP2D6CA12CA4CA6CA5A | |
| SCHEMBL30871996 | 0.75 | KDM4E (0.69) | MMP9MMP13MMP2MMP8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486624-A | FREE RADICAL SCAVENGERS, TYROSINASE INHIBITORS | PACIFIC CORPORATION (KR) | 1996-01-23 | — | — | US | disclosed |