Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993609 | 0.86 | MMP9 (0.57) | APPHSD17B10KDM4EMAPTTDP1 | |
| SCHEMBL2491005 | 0.73 | KDM4E (0.47) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL8365088 | 0.72 | IAPP (0.64) | APPHSD17B10KDM4EPTPN1MAPT | |
| SCHEMBL29216356 | 0.71 | HSD17B10 (0.64) | APPHSD17B10KDM4EPTPN1MAPT | |
| SCHEMBL8993664 | 0.71 | PPARG (0.59) | APPHSD17B10KDM4EPTPN1MAPT | |
| SCHEMBL8993669 | 0.71 | PPARG (0.59) | APPHSD17B10KDM4EPTPN1MAPT | |
| SCHEMBL29345014 | 0.70 | IAPP (0.66) | APPHSD17B10KDM4EPTPN1MAPT | |
| SCHEMBL15981545 | 0.70 | IAPP (0.66) | APPHSD17B10KDM4EPTPN1MAPT | |
| Caffeic Acid SCHEMBL31606906 | 0.68 | KDM4E (0.96) | APPHSD17B10KDM4EPTPN1MAPT | |
| SCHEMBL2221673 | 0.68 | KDM4E (0.74) | APPHSD17B10KDM4EPTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486624-A | FREE RADICAL SCAVENGERS, TYROSINASE INHIBITORS | PACIFIC CORPORATION (KR) | 1996-01-23 | — | — | US | disclosed |