SCHEMBL8993618

SCHEMBL8993618

CCCCC(CC=O)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
CTSK P43235 1/20 0.34
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19385831 0.95 CA2 (0.34) CA2CTSKTSHR
SCHEMBL9865913 0.94 ADH1B (0.34) CA2CTSKTSHR
SCHEMBL12083819 0.94 ADH1B (0.34) CA2CTSKTSHR
SCHEMBL4136407 0.94 ADH1B (0.34) CA2CTSKTSHR
SCHEMBL9031315 0.94 ADH1B (0.34) CA2CTSKTSHR
SCHEMBL9031307 0.94 ADH1B (0.34) CA2CTSKTSHR
SCHEMBL12083670 0.94 ADH1B (0.34) CA2CTSKTSHR
SCHEMBL4136401 0.94 ADH1B (0.34) CA2CTSKTSHR
SCHEMBL18194652 0.90 CA2 (0.32) CA2
SCHEMBL16177605 0.85 CA2 (0.37) CA2CTSKTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5504108-A ANTIAGGLOMERANTS, ANTIARTHRITIC AGENTS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1996-04-02 US disclosed
WO-1995023139-A1 OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1995-08-31 WO disclosed
US-5399721-A Anticoagulant; prepared from aldehyde THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1995-03-21 US disclosed