Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.43 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807362 | 0.88 | TDP1 (0.52) | TDP1CTSBNOTUML3MBTL1ALDH1A1 | |
| SCHEMBL8993507 | 0.82 | GABRA1 (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL24152419 | 0.80 | TDP1 (0.60) | TDP1CTSBNOTUML3MBTL1ALDH1A1 | |
| SCHEMBL29938053 | 0.80 | TDP1 (0.60) | TDP1CTSBNOTUML3MBTL1ALDH1A1 | |
| SCHEMBL9423041 | 0.79 | TDP1 (0.40) | TDP1CTSBNOTUML3MBTL1ALDH1A1 | |
| SCHEMBL9168174 | 0.79 | TDP1 (0.40) | TDP1CTSBNOTUML3MBTL1ALDH1A1 | |
| SCHEMBL29576263 | 0.79 | TDP1 (0.40) | TDP1CTSBNOTUML3MBTL1ALDH1A1 | |
| SCHEMBL9262971 | 0.78 | TDP1 (0.55) | TDP1CTSBNOTUML3MBTL1ALDH1A1 | |
| SCHEMBL6465173 | 0.78 | LMNA (0.47) | TDP1CTSBNOTUML3MBTL1ALDH1A1 | |
| Ethylene SCHEMBL9423310 | 0.77 | TDP1 (0.39) | TDP1CTSBNOTUML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527764-A | 3-arylthionouracils useful as herbicides, defoliants, and desiccants | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1996-06-18 | — | — | US | disclosed |