Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.62 |
| ▸ | F2 | P00734 | 8/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.54 |
| ▸ | PLG | P00747 | 2/20 | 0.54 |
| ▸ | PROC | P04070 | 2/20 | 0.54 |
| ▸ | PLAT | P00750 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993757 | 0.99 | F10 (0.65) | F10F2PRSS1PLGPROC | |
| SCHEMBL8993813 | 0.96 | F10 (0.65) | F10F2PRSS1PLGPROC | |
| SCHEMBL8993808 | 0.95 | F10 (0.68) | F10F2PRSS1PLGPROC | |
| SCHEMBL8993720 | 0.94 | F2 (0.57) | F10F2PRSS1PLGPROC | |
| SCHEMBL8993756 | 0.93 | F2 (0.58) | F10F2PRSS1PLGPROC | |
| SCHEMBL8993746 | 0.92 | F10 (0.66) | F10F2PRSS1PLGPROC | |
| SCHEMBL8993726 | 0.92 | F10 (0.52) | F10F2PRSS1PLGPROC | |
| SCHEMBL8993691 | 0.91 | F2 (0.64) | F10F2PRSS1PLGPROC | |
| SCHEMBL8993684 | 0.90 | F10 (0.69) | F10F2PRSS1PLGPROC | |
| SCHEMBL8993699 | 0.90 | F10 (0.59) | F10F2PRSS1PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489583-A | FOR TREATING OR PREVENTING THROMBOSIS | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-06 | — | — | US | disclosed |