SCHEMBL8993746

SCHEMBL8993746

COc1ccc2cc(S(=O)(=O)NC3CCCN(C(Cc4ccc(C(=N)N)cc4)C(=O)O)C3=O)ccc2c1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.66
F2 P00734 7/20 0.59
PRSS1 P07477 3/20 0.57
PLG P00747 2/20 0.57
PROC P04070 2/20 0.57
PLAT P00750 1/20 0.57
KLK6 Q92876 1/20 0.54
PRSS2 P07478 1/20 0.54
PRSS3 P35030 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8993684 0.98 F10 (0.69) F10F2PRSS1PLGPROC
SCHEMBL8993800 0.95 F10 (0.70) F10F2PRSS1PLGPROC
SCHEMBL8993724 0.94 F10 (0.73) F10F2PRSS1PLGPROC
SCHEMBL8993698 0.93 F10 (0.59) F10F2PRSS1PLGPROC
SCHEMBL8993733 0.93 F10 (0.63) F10F2PRSS1PLGPROC
SCHEMBL8993703 0.92 F10 (0.62) F10F2PRSS1PLGPROC
SCHEMBL8993727 0.91 F10 (0.55) F10F2PRSS1PLGPROC
SCHEMBL8993723 0.91 F10 (0.65) F10F2PRSS1PLGPROC
SCHEMBL8993757 0.91 F10 (0.65) F10F2PRSS1PLGPROC
SCHEMBL8993790 0.90 F2 (0.66) F10F2PRSS1PLGPROC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489583-A FOR TREATING OR PREVENTING THROMBOSIS BASF AKTIENGESELLSCHAFT (DE) 1996-02-06 US disclosed