SCHEMBL8993949

SCHEMBL8993949

O=C1C=C(C(=O)O)CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6781313 0.79
SCHEMBL18137236 0.73 ITGB3 (0.39)
SCHEMBL11498473 0.68 TSHR (0.45)
SCHEMBL8007269 0.68 TSHR (0.36)
SCHEMBL29816130 0.67 MAOA (0.35)
SCHEMBL30672507 0.67 TSHR (0.32)
SCHEMBL980578 0.67 MAOA (0.35)
Hydrochloric Acid SCHEMBL27489771 0.66 BLM (0.34)
Hydrochloric Acid SCHEMBL3719374 0.66 BLM (0.34)
SCHEMBL27190625 0.65 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013123403-A1 THERANOSTICS PLATFORM AND METHODS OF USE SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2013-08-22 WO disclosed
EP-0724606-A1 PREPARATION OF POLY(ETHER-ESTERS) FROM TETRAHYDROFURANS AND POLYCARBOXYLIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-07 EP disclosed
WO-1995011267-A1 PREPARATION OF POLY(ETHER-ESTERS) FROM TETRAHYDROFURANS AND POLYCARBOXYLIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-04-27 WO disclosed