SCHEMBL8993968

SCHEMBL8993968

CC(C)(C)OC(=O)N1CCC(CN)CC1.CNC1CCNCC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.45
KDM4E B2RXH2 2/20 0.44
PKM P14618 1/20 0.44
HPGD P15428 1/20 0.41
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
NPC1 O15118 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
RECQL P46063 1/20 0.40
DPP4 P27487 1/20 0.39
THRB P10828 1/20 0.39
PTPN2 P17706 1/20 0.39
PTPN1 P18031 1/20 0.39
PTPN6 P29350 1/20 0.39
NR1H2 P55055 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8993970 0.90 HPGD (0.47) EPHX1KDM4EPKMHPGDMAPT
SCHEMBL103083 0.84 HPGD (0.54) EPHX1KDM4EPKMHPGDMAPT
Hydrochloric Acid SCHEMBL735395 0.83 HPGD (0.53) EPHX1KDM4EPKMHPGDMAPT
SCHEMBL15000860 0.80 GNAI3 (0.51) EPHX1KDM4EPKMHPGDMAPT
SCHEMBL215297 0.80 EPHX1 (0.65) EPHX1KDM4EPKMHPGDALDH1A1
SCHEMBL1155492 0.79 EPHX1 (0.57) EPHX1KDM4EHPGDALDH1A1MAPT
Hydrochloric Acid SCHEMBL1532657 0.79 GNAI3 (0.53) EPHX1KDM4EPKMHPGDMAPT
SCHEMBL4038117 0.79 HPGD (0.49) EPHX1KDM4EPKMHPGDMAPT
SCHEMBL17221591 0.79 HPGD (0.56) EPHX1KDM4EPKMHPGDALDH1A1
SCHEMBL8993972 0.78 KDM4E (0.54) EPHX1KDM4EPKMHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0725059-A1 2,3-DIAMINOPROPIONIC ACID DERIVATIVE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1996-08-07 EP disclosed