Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15000860 | 0.88 | GNAI3 (0.51) | KDM4EPKMEPHX1MAPTTHRB | |
| SCHEMBL4038117 | 0.87 | HPGD (0.49) | KDM4EPKMEPHX1MAPTTHRB | |
| Hydrochloric Acid SCHEMBL1532657 | 0.87 | GNAI3 (0.53) | KDM4EPKMEPHX1MAPTTHRB | |
| SCHEMBL1532854 | 0.86 | ITGB3 (0.55) | KDM4EPKMHPGDGPR119 | |
| SCHEMBL27124589 | 0.84 | HPGD (0.47) | KDM4EPKMEPHX1MAPTTHRB | |
| SCHEMBL8993970 | 0.84 | HPGD (0.47) | KDM4EPKMEPHX1MAPTTHRB | |
| SCHEMBL5573225 | 0.84 | KDM4E (0.63) | KDM4EPKMEPHX1HPGDTGFBR1 | |
| Acetic Acid SCHEMBL31129712 | 0.83 | KDM4E (0.48) | KDM4EPKMEPHX1MAPTTHRB | |
| Acetic Acid SCHEMBL31129570 | 0.83 | KDM4E (0.48) | KDM4EPKMEPHX1MAPTTHRB | |
| SCHEMBL18921639 | 0.82 | HPGD (0.51) | KDM4EPKMEPHX1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |