Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Cyanophenol SCHEMBL8994006 | 0.96 | MMP3 (0.52) | CYSLTR2CYSLTR1MAPTHRH2HRH1 | |
| SCHEMBL6328916 | 0.94 | MAPT (0.55) | CYSLTR2CYSLTR1MAPTHRH2HRH1 | |
| SCHEMBL1285386 | 0.90 | MMP2 (0.61) | CYSLTR2CYSLTR1MAPTHRH2HRH1 | |
| SCHEMBL1285929 | 0.90 | MMP2 (0.61) | CYSLTR2CYSLTR1MAPTHRH2HRH1 | |
| SCHEMBL7301892 | 0.90 | MMP3 (0.57) | CYSLTR2CYSLTR1MAPTHRH2HRH1 | |
| SCHEMBL3466988 | 0.90 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1MAPTBRD4ALDH2 | |
| SCHEMBL5522757 | 0.89 | HDAC1 (0.58) | CYSLTR2CYSLTR1MAPTHRH2HRH1 | |
| SCHEMBL6336869 | 0.89 | HDAC1 (0.58) | CYSLTR2CYSLTR1MAPTHRH2HRH1 | |
| SCHEMBL15970987 | 0.87 | MMP2 (0.59) | MAPTHRH2HRH1HRH3ALDH1A1 | |
| SCHEMBL7717980 | 0.87 | PPARD (0.51) | CYSLTR2CYSLTR1MAPTHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |