Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 6/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589716 | 0.80 | MMP2 (0.58) | MMP2MMP8MMP14FDPSRAB9A | |
| SCHEMBL8588143 | 0.78 | MMP2 (0.59) | MMP2MMP8MMP14SLC6A4FDPS | |
| SCHEMBL8994333 | 0.77 | SLC6A4 (0.43) | SLC6A4FDPSSERPINE1RAB9ATHRB | |
| SCHEMBL2149971 | 0.72 | MMP2 (0.66) | MMP2MMP8MMP14SLC6A4FDPS | |
| SCHEMBL10788079 | 0.72 | MMP8 (0.66) | MMP2MMP8MMP14FDPSMMP1 | |
| SCHEMBL8589347 | 0.72 | MMP2 (0.66) | MMP2MMP8MMP14SLC6A4FDPS | |
| SCHEMBL8070325 | 0.72 | SLC6A4 (0.54) | SLC6A4SERPINE1RAB9ATHRBTHRA | |
| SCHEMBL8589189 | 0.72 | SLC6A4 (0.39) | SLC6A4FDPSSERPINE1RAB9ATHRB | |
| SCHEMBL8994328 | 0.72 | MMP2 (0.44) | MMP2MMP8MMP14FDPSMMP1 | |
| SCHEMBL8588324 | 0.72 | SLC6A4 (0.58) | SLC6A4SERPINE1RAB9ATHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527940-A | SUPPRESSES INTERLEUKIN-1 AND BONE DESTRUCTION DURING OSTEOPOROSIS; ANTIINFLAMMATORY AGENTS | TORAY INDUSTRIES, INC. (JP) | 1996-06-18 | — | — | US | disclosed |