Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366799 | 0.83 | POLB (0.63) | POLBPARP1VNN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7370711 | 0.83 | POLB (0.63) | POLBPARP1VNN1ALDH1A1KDM4E | |
| SCHEMBL8994491 | 0.83 | KDM4E (0.58) | POLBALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL9045871 | 0.81 | POLB (0.46) | POLBPARP1VNN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8994512 | 0.81 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1KDM4EMAPTNPSR1 | |
| SCHEMBL186545 | 0.76 | PARP1 (0.68) | POLBPARP1SMN1; SMN2HPGDHDAC8 | |
| SCHEMBL29503529 | 0.76 | PARP1 (0.68) | POLBPARP1SMN1; SMN2HPGDHDAC8 | |
| SCHEMBL81347 | 0.75 | ATM (0.71) | POLBPARP1VNN1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4636828 | 0.75 | PARP1 (0.61) | POLBPARP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29658753 | 0.75 | ATM (0.71) | POLBPARP1VNN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512564-A | VIRICIDES, AIDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-30 | — | — | US | disclosed |
| EP-0602097-B1 | TRICYCLIC THIAZOL AND OXAZOL DERIVATES WITH ANTIVIRAL ACTION | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-24 | — | — | EP | disclosed |
| EP-0602097-A1 | NEW TRICYCLIC THIAZOL AND OXAZOL DERIVATES WITH ANTIVIRAL ACTION. | BOEHRINGER MANNHEIM GMBH (DE) | 1994-06-22 | — | — | EP | disclosed |
| WO-1993005047-A1 | NEW TRICYCLIC THIAZOL AND OXAZOL DERIVATES WITH ANTIVIRAL ACTION | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-18 | — | — | WO | disclosed |