Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 18/20 | 0.55 |
| ▸ | CTRC | Q99895 | 3/20 | 0.43 |
| ▸ | CMA1 | P23946 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274001 | 0.88 | ELANE (0.61) | ELANECTRC | |
| SCHEMBL7399566 | 0.87 | ELANE (0.62) | ELANECTRCCMA1 | |
| SCHEMBL7547030 | 0.87 | ELANE (0.62) | ELANECTRC | |
| SCHEMBL7546824 | 0.82 | ELANE (0.54) | ELANECTRC | |
| SCHEMBL7392881 | 0.82 | ELANE (0.56) | ELANECTRCCMA1 | |
| SCHEMBL6556228 | 0.80 | ELANE (0.54) | ELANECTRCCMA1 | |
| SCHEMBL7547485 | 0.79 | ELANE (0.75) | ELANECTRC | |
| SCHEMBL7552480 | 0.79 | ELANE (0.64) | ELANECTRCCMA1 | |
| SCHEMBL7399564 | 0.77 | ELANE (0.53) | ELANECTRCCMA1 | |
| SCHEMBL7276466 | 0.77 | ELANE (0.64) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486529-A | Certain pyridyl ketones for treating diseases involving leukocyte elastase | ZENECA LIMITED (GB) | 1996-01-23 | — | — | US | disclosed |