Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.49 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | CTRC | Q99895 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552480 | 0.88 | ELANE (0.64) | ELANECMA1CTRC | |
| SCHEMBL7548502 | 0.83 | ELANE (0.71) | ELANECTRC | |
| SCHEMBL7399566 | 0.80 | ELANE (0.62) | ELANECMA1CTRC | |
| SCHEMBL7398791 | 0.78 | CTRC (0.57) | ELANECMA1CTRC | |
| SCHEMBL8536332 | 0.77 | ELANE (0.71) | ELANECTRC | |
| SCHEMBL7399002 | 0.76 | ELANE (0.66) | ELANECTRC | |
| SCHEMBL7394151 | 0.75 | KDM4E (0.35) | — | |
| SCHEMBL8994502 | 0.73 | ELANE (0.65) | ELANECTRC | |
| SCHEMBL7283009 | 0.71 | ELANE (0.52) | ELANECTRC | |
| SCHEMBL7276644 | 0.70 | ELANE (0.76) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486529-A | Certain pyridyl ketones for treating diseases involving leukocyte elastase | ZENECA LIMITED (GB) | 1996-01-23 | — | — | US | disclosed |