Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.58 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753562 | 0.89 | ALOX5 (0.59) | ALOX5ESR2BACE1ESR1ALDH1A1 | |
| SCHEMBL28526907 | 0.89 | ALOX5 (0.59) | ALOX5ESR2BACE1ESR1ALDH1A1 | |
| SCHEMBL9247179 | 0.86 | ESR2 (0.56) | ALOX5ESR2ESR1ALDH1A1NR1I2 | |
| SCHEMBL29978461 | 0.85 | ALOX5 (0.53) | ALOX5ESR2BACE1ESR1ALDH1A1 | |
| SCHEMBL674204 | 0.85 | ALOX5 (0.53) | ALOX5ESR2BACE1ESR1ALDH1A1 | |
| SCHEMBL1802128 | 0.81 | ALOX5 (0.59) | ALOX5ESR2BACE1ESR1HSP90AA1 | |
| Chloromethane SCHEMBL28112788 | 0.78 | ALOX5 (0.87) | ALOX5ESR2BACE1ESR1ALDH1A1 | |
| SCHEMBL28243339 | 0.76 | ESR2 (0.62) | ALOX5ESR2ESR1ALDH1A1LMNA | |
| SCHEMBL7855632 | 0.76 | HSD17B10 (0.57) | ALOX5ESR2ESR1ALDH1A1NR1I2 | |
| SCHEMBL344517 | 0.76 | ABL1 (0.50) | ALOX5ESR2BACE1ESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604056-B1 | Bis[4'-(4-hydroxyphenyl)-phenyl]alkanes and polycarbonates prepared therefrom | GEN ELECTRIC (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0604056-A2 | Bis[4'-(4-hydroxyphenyl)-phenyl]alkanes and polycarbonates prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5319149-A | Bis[4'-(4-hydroxyphenyl)-phenyl]alkanes and polycarbonates prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| US-5281689-A | Polycarbonate from bis[4'-(4-hydroxyphenyl)-phenyl]alkanes | GENERAL ELECTRIC COMPANY (US) | 1994-01-25 | — | — | US | disclosed |