Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28415938 | 0.88 | HSD17B1 (0.59) | ALOX5HSD17B1HSD17B2ESR2AR | |
| SCHEMBL31256038 | 0.83 | GLA (0.54) | ALOX5HSD17B1HSD17B2ESR2AR | |
| SCHEMBL5792355 | 0.83 | GLA (0.54) | ALOX5HSD17B1HSD17B2ESR2AR | |
| SCHEMBL27870662 | 0.83 | HSD17B1 (0.55) | HSD17B1HSD17B2ESR2MEN1KMT2A | |
| SCHEMBL9830978 | 0.83 | HSD17B1 (0.52) | ALOX5HSD17B1HSD17B2PDK2 | |
| SCHEMBL4224790 | 0.81 | HSD17B1 (0.57) | HSD17B1HSD17B2ESR2CNR1CNR2 | |
| SCHEMBL14832293 | 0.81 | CYP11B1 (0.56) | HSD17B1HSD17B2MAPTS1PR1S1PR3 | |
| SCHEMBL30753562 | 0.81 | ALOX5 (0.59) | ALOX5HSD17B1HSD17B2ESR2KMT2A | |
| SCHEMBL28526907 | 0.81 | ALOX5 (0.59) | ALOX5HSD17B1HSD17B2ESR2KMT2A | |
| SCHEMBL8994507 | 0.81 | ALOX5 (0.59) | ALOX5HSD17B1HSD17B2ESR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011054530-A1 | GPBP INHIBITION USING Q2 PEPTIDOMIMETICS | FIBROSTATIN, S.L. (ES) | 2011-05-12 | — | — | WO | claimed |
| EP-1758853-B1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | LILLY CO ELI (US) | 2010-01-20 | — | — | EP | disclosed |
| US-20090221547-A1 | Immunosuppressant Compounds and Compositions | IRM LLC (BM) | 2009-09-03 | — | — | US | disclosed |
| US-20090221547-A1 | Immunosuppressant Compounds and Compositions | IRM LLC (BM) | 2009-09-03 | — | — | US | disclosed |
| US-20090221547-A1 | Immunosuppressant Compounds and Compositions | IRM LLC (BM) | 2009-09-03 | — | — | US | disclosed |
| CN-101291908-A | Immunosuppressant compounds and compositions | IRM LLC (BM) | 2008-10-22 | — | — | CN | disclosed |
| EP-1917240-A1 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-05-07 | — | — | EP | disclosed |
| EP-1758853-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2007024922-A1 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2007-03-01 | — | — | WO | disclosed |
| WO-2007024922-A1 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2007-03-01 | — | — | WO | disclosed |
| WO-2005123668-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-29 | — | — | WO | disclosed |
| CN-1088453-C | Fluorine-substituted liquid-crystal compound, liquid-crystal composition and liquid-crystal display device | CHISSO CORP (JP) | 2002-07-31 | — | — | CN | disclosed |
| CN-1184462-A | Fluorine-substituted liquid-crystal compound, liquid-crystal composition and liquid-crystal display device | CHISSO CORP (JP) | 1998-06-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221547-A1 | Immunosuppressant Compounds and Compositions | ICOS, EDNRA, ICOSLG | ALOX5 294/4885HSD17B1 1359/4885HSD17B2 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.