Sugi Predict

Sugi Predict / Compounds / SCHEMBL8994541

SCHEMBL8994541

SCHEMBL8994541

Cc1cccc(COC(=O)Nc2ccc(-c3ccccc3)n(CC(=O)NC(O[SiH](C)C)(C(C)C)C(C(C)(C)C)C(F)(F)C(=O)NCCc3ccccc3)c2=O)n1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 20/20 0.51
▸ CTRC Q99895 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994526 0.92 ELANE (0.58) ELANECTRC
SCHEMBL7545819 0.84 ELANE (0.58) ELANECTRC
SCHEMBL7437149 0.82 ELANE (0.50) ELANECTRC
SCHEMBL7276063 0.82 ELANE (0.62) ELANECTRC
SCHEMBL7546824 0.82 ELANE (0.54) ELANECTRC
SCHEMBL7440506 0.82 ELANE (0.68) ELANECTRC
SCHEMBL9011657 0.79 ELANE (0.65) ELANECTRC
SCHEMBL9011680 0.78 ELANE (0.55) ELANECTRC
SCHEMBL7286150 0.77 ELANE (0.65) ELANECTRC
SCHEMBL7277026 0.77 ELANE (0.59) ELANECTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486529-A Certain pyridyl ketones for treating diseases involving leukocyte elastase ZENECA LIMITED (GB) 1996-01-23 — — US disclosed