Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377969 | 0.79 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL122974 | 0.79 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL29352462 | 0.79 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL4977962 | 0.77 | ESR1 (0.50) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL14445708 | 0.76 | ALDH1A1 (0.69) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL225599 | 0.75 | ALDH1A1 (0.48) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL29829219 | 0.74 | ALDH1A1 (0.55) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL1972339 | 0.74 | ALDH1A1 (0.55) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL109921 | 0.73 | ALDH1A1 (0.67) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL29364103 | 0.73 | ALDH1A1 (0.67) | ALDH1A1ALOX15HSD17B10NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987006-A | LITHIUM INITIATED, COUPLED POLYMER | PHILLIPS PETROLEUM COMPANY (US) | 1976-10-19 | — | — | US | claimed |
| EP-0492490-B1 | Tapered block styrene/butadiene copolymers | PHILLIPS PETROLEUM CO (US) | 1996-08-14 | — | — | EP | disclosed |
| US-5227419-A | TAPERED BLOCK STYRENE/BUTADIENE COPOLYMERS | PHILLIPS PETROLEUM COMPANY (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0492490-A2 | Tapered block styrene/butadiene copolymers | PHILLIPS PETROLEUM COMPANY (US) | 1992-07-01 | — | — | EP | disclosed |