SCHEMBL8994676

SCHEMBL8994676

CCO/C=C(\OCC)C(=O)Oc1ccc(OC(=O)/C(=C/OCC)OCC)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 11/20 0.38
MEN1 O00255 6/20 0.38
MAPT P10636 5/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 2/20 0.38
HSP90AA1 P07900 1/20 0.38
HPGD P15428 1/20 0.38
LMNA P02545 3/20 0.36
THRB P10828 1/20 0.36
GLA P06280 1/20 0.36
PRSS1 P07477 1/20 0.35
ACR P10323 1/20 0.35
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ESR1 P03372 1/20 0.35
RECQL P46063 1/20 0.35
HIF1A Q16665 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994678 1.00 KMT2A (0.38) KMT2AMEN1MAPTALDH1A1KDM4E
SCHEMBL20556082 0.92 MAPT (0.46) KMT2AMEN1MAPTALDH1A1KDM4E
SCHEMBL20556083 0.92 MAPT (0.46) KMT2AMEN1MAPTALDH1A1KDM4E
SCHEMBL6074988 0.79 NPSR1 (0.43) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL2778172 0.79 NPSR1 (0.43) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL27579481 0.77 MAPT (0.50) KMT2AMEN1MAPTALDH1A1KDM4E
SCHEMBL28697143 0.76 ALDH1A1 (0.37) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL4108086 0.75 L3MBTL1 (0.41) KMT2AMEN1ALDH1A1KDM4ELMNA
SCHEMBL28787713 0.73 ALDH1A1 (0.34) KMT2AMEN1ALDH1A1LMNASMN1; SMN2
SCHEMBL27818760 0.73 HCAR2 (0.37) ALDH1A1LMNATHRBTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0556851-B1 Method of splicing metal webs FUJI PHOTO FILM CO LTD (JP) 1996-08-21 EP disclosed
EP-0556851-A1 Method of splicing metal webs FUJI PHOTO FILM CO., LTD. (JP) 1993-08-25 EP disclosed
US-4294905-A DIAZO COMPOUNDS, OLEOPHILIC AND STORAGE STABLE FUJI PHOTO FILM CO., LTD. (JP) 1981-10-13 US disclosed