Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.67 |
| ▸ | DRD1 | P21728 | 4/20 | 0.67 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.62 |
| ▸ | DRD4 | P21917 | 4/20 | 0.62 |
| ▸ | HTR1A | P08908 | 5/20 | 0.61 |
| ▸ | HTR2A | P28223 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 2/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928151 | 0.89 | DRD4 (0.76) | DRD2DRD1HRH4DRD4HTR1A | |
| SCHEMBL29623704 | 0.86 | DRD2 (0.90) | DRD2DRD1HRH4DRD4HTR1A | |
| SCHEMBL8204163 | 0.86 | DRD2 (0.64) | DRD2DRD1HRH4DRD4HTR1A | |
| SCHEMBL8928035 | 0.84 | HRH4 (0.62) | DRD2DRD1HRH4DRD4HTR1A | |
| SCHEMBL8204367 | 0.83 | DRD1 (0.55) | DRD2DRD1HRH4DRD4HTR1A | |
| SCHEMBL8928029 | 0.82 | DRD4 (0.61) | DRD2DRD1HRH4DRD4HTR1A | |
| SCHEMBL8204496 | 0.82 | DRD2 (0.77) | DRD2DRD1HRH4DRD4HTR1A | |
| SCHEMBL8203868 | 0.81 | DRD2 (0.76) | DRD2DRD1HRH4DRD4HTR1A | |
| SCHEMBL4192075 | 0.81 | HRH4 (0.83) | DRD2DRD1HRH4DRD4HTR1A | |
| Hydrochloric Acid SCHEMBL3838758 | 0.80 | HRH4 (0.81) | DRD2DRD1HRH4DRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538965-A | TREATMENT OF PSYCHOLOGICAL DISORDERS SUCH AS SCHIZOPHRENIA AND ANXIETY | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1996-07-23 | — | — | US | claimed |