SCHEMBL8994875

SCHEMBL8994875

c1ccc(N(c2ccc(-c3cccs3)cc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccc(-c5cccs5)cc4)s3)s2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.46
LTA4H P09960 2/20 0.41
CYP17A1 P05093 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
MAPT P10636 4/20 0.37
KCNH2 Q12809 1/20 0.37
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
GAA P10253 2/20 0.35
MEN1 O00255 1/20 0.35
HCRTR1 O43613 1/20 0.35
NFKB1 P19838 1/20 0.35
CASP3 P42574 1/20 0.35
NFKB2 Q00653 1/20 0.35
KMT2A Q03164 1/20 0.35
RELA Q04206 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994689 0.94 LTA4H (0.43) APPLTA4HCYP17A1CYP11B1CYP11B2
SCHEMBL867469 0.85 LTA4H (0.50) APPLTA4HCYP17A1CYP11B1CYP11B2
SCHEMBL14253104 0.85 LTA4H (0.50) APPLTA4HCYP17A1CYP11B1CYP11B2
SCHEMBL12180541 0.84 APP (0.59) APPLTA4HMAPTKDM4EALDH1A1
SCHEMBL12180504 0.84 APP (0.59) APPLTA4HMAPTKDM4EALDH1A1
SCHEMBL8994780 0.83 APP (0.49) APPMAPTKDM4EALDH1A1NPC1
SCHEMBL15591131 0.83 LTA4H (0.48) APPLTA4HCYP17A1CYP11B1CYP11B2
SCHEMBL18193947 0.82 APP (0.55) APPMAPTKDM4EALDH1A1RAB9A
SCHEMBL18382266 0.82 APP (0.51) APPMAPTKDM4EALDH1A1NPC1
SCHEMBL12372897 0.82 APP (0.51) APPLTA4HCYP17A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187728-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2012-05-29 US disclosed
US-8187728-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2012-05-29 US disclosed
US-20090026935-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2009-01-29 US disclosed
US-20090026935-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2009-01-29 US disclosed