Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 4/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13197641 | 0.96 | APP (0.51) | APPLTA4HDPP4CYP17A1CYP11B1 | |
| SCHEMBL2864395 | 0.96 | APP (0.51) | APPLTA4HDPP4CYP17A1CYP11B1 | |
| SCHEMBL12180504 | 0.91 | APP (0.59) | APPLTA4HDPP4MAPTKDM4E | |
| SCHEMBL12180541 | 0.91 | APP (0.59) | APPLTA4HDPP4MAPTKDM4E | |
| SCHEMBL8014120 | 0.90 | LTA4H (0.55) | APPLTA4HCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL2344484 | 0.90 | LTA4H (0.55) | APPLTA4HCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL18194039 | 0.90 | CYP17A1 (0.53) | APPLTA4HDPP4CYP17A1CYP11B1 | |
| SCHEMBL12893283 | 0.89 | APP (0.46) | APPLTA4HDPP4CYP17A1CYP11B1 | |
| SCHEMBL14565390 | 0.89 | APP (0.46) | APPLTA4HDPP4MAPTKDM4E | |
| SCHEMBL14192249 | 0.88 | LTA4H (0.53) | APPLTA4HCYP17A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9112167-B2 | Aromatic amine derivatives and organic electroluminescent device using same | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2015-08-18 | — | — | US | disclosed |
| US-9112167-B2 | Aromatic amine derivatives and organic electroluminescent device using same | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2015-08-18 | — | — | US | disclosed |
| US-20140077200-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | SONY CORPORATION (JP) | 2014-03-20 | — | — | US | disclosed |
| US-20140077200-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | SONY CORPORATION (JP) | 2014-03-20 | — | — | US | disclosed |
| US-7998596-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-7998596-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20080108832-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-05-08 | — | — | US | disclosed |
| US-20080108832-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108832-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | ALKBH3, EML4, ALKBH2 | APP 281/4885LTA4H 1751/4885DPP4 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.