Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.76 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.64 |
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.52 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.52 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.52 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | S100B | P04271 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8995070 | 0.99 | LTB4R (0.74) | LTB4RLTB4R2PRSS1F2ST14 | |
| Hydrochloric Acid SCHEMBL8994957 | 0.96 | LTB4R (0.69) | LTB4RLTB4R2PRSS1F2ST14 | |
| Hydrochloric Acid SCHEMBL8995026 | 0.91 | LTB4R (0.71) | LTB4RLTB4R2PRSS1F2ST14 | |
| Hydrochloric Acid SCHEMBL8994899 | 0.88 | LTB4R (0.77) | LTB4RLTB4R2PRSS1F2ST14 | |
| Moxilubant SCHEMBL29388138 | 0.86 | LTB4R (1.00) | LTB4RLTB4R2PRSS1F2ST14 | |
| Moxilubant SCHEMBL6439215 | 0.86 | LTB4R (1.00) | LTB4RLTB4R2PRSS1F2ST14 | |
| Moxilubant SCHEMBL8994884 | 0.85 | LTB4R (0.98) | LTB4RLTB4R2PRSS1F2ST14 | |
| Hydrochloric Acid SCHEMBL8994944 | 0.85 | PRSS1 (0.68) | PRSS1F2ST14PLAUPRMT1 | |
| SCHEMBL8994962 | 0.83 | LTB4R (0.54) | LTB4RLTB4R2PRSS1ACHEPLA2G4B | |
| Hydrochloric Acid SCHEMBL8995010 | 0.83 | LTB4R (0.69) | LTB4RLTB4R2PRSS1F2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | claimed |
| EP-0518819-B1 | Amidino compounds, their manufacture and use as medicament | CIBA GEIGY AG (CH) | 1995-08-02 | — | — | EP | claimed |
| EP-0518819-A2 | Amidino compounds, their manufacture and use as medicament | CIBA-GEIGY AG (CH) | 1992-12-16 | — | — | EP | claimed |