Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.67 |
| ▸ | NOS1 | P29475 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131855 | 0.93 | TBXAS1 (0.70) | MEN1KMT2ATBXAS1NOS1KDM4E | |
| Hydrochloric Acid SCHEMBL2529362 | 0.88 | MEN1 (0.85) | QPCTMEN1KMT2AATMTBXAS1 | |
| Hydrochloric Acid SCHEMBL9482694 | 0.83 | ATP4A (0.69) | QPCTMEN1KMT2AATMTBXAS1 | |
| Hydrochloric Acid SCHEMBL9482687 | 0.83 | ATP4A (0.69) | QPCTMEN1KMT2AATMTBXAS1 | |
| SCHEMBL8995204 | 0.83 | TBXAS1 (0.51) | QPCTMEN1KMT2ATBXAS1KDM4E | |
| SCHEMBL8995361 | 0.82 | QPCT (0.69) | QPCTMEN1KMT2AATMTBXAS1 | |
| SCHEMBL10457427 | 0.82 | QPCT (0.73) | QPCTMEN1KMT2AATMTBXAS1 | |
| SCHEMBL6302835 | 0.82 | QPCT (0.73) | QPCTMEN1KMT2AATMTBXAS1 | |
| SCHEMBL18837209 | 0.82 | QPCT (0.73) | QPCTMEN1KMT2AATMTBXAS1 | |
| SCHEMBL8684902 | 0.82 | QPCT (0.73) | QPCTMEN1KMT2AATMTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496844-A | Indole derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0639567-A1 | INDOLE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-02-22 | — | — | EP | disclosed |