Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762320 | 1.00 | METAP2 (0.54) | METAP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5264997 | 0.90 | MEN1 (0.61) | METAP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9267426 | 0.90 | MEN1 (0.61) | METAP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11669294 | 0.87 | SPHK1 (0.66) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL10791327 | 0.86 | MEN1 (0.60) | METAP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5270163 | 0.86 | MEN1 (0.60) | METAP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14209990 | 0.86 | MEN1 (0.60) | METAP2MEN1KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL10371302 | 0.84 | MEN1 (0.58) | METAP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20243040 | 0.83 | LTA4H (0.68) | S1PR1S1PR3LTA4HGAAPOLB | |
| SCHEMBL2522626 | 0.83 | LTA4H (0.68) | S1PR1S1PR3LTA4HGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494716-B1 | Enzyme-catalysed preparation of optically active carboxylic acids | DSM NV (NL) | 1996-08-28 | — | — | EP | disclosed |
| US-5248608-A | Enzyme catalyzed stereospecific hdyrolysis | DSM N.V. (NL) | 1993-09-28 | — | — | US | disclosed |
| EP-0494716-A2 | Enzyme-catalysed preparation of optically active carboxylic acids | DSM N.V. (NL) | 1992-07-15 | — | — | EP | disclosed |