SCHEMBL8995870

SCHEMBL8995870

CCOC(=O)c1ccccc1N=[N]

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.67
HSD17B10 Q99714 3/20 0.57
ALDH1A1 P00352 3/20 0.57
ACHE P22303 1/20 0.51
KMT2A Q03164 2/20 0.49
CDC25B P30305 2/20 0.49
CYP3A4 P08684 2/20 0.49
LMNA P02545 1/20 0.49
MEN1 O00255 1/20 0.49
USP2 O75604 1/20 0.49
CYP1A2 P05177 1/20 0.49
MAPT P10636 1/20 0.49
CYP2C9 P11712 1/20 0.49
ALOX15 P16050 1/20 0.49
CYP2C19 P33261 1/20 0.49
MAPK10 P53779 1/20 0.49
PTK2B Q14289 1/20 0.49
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49
PDK2 Q15119 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7992543 0.84 TSHR (0.69) TSHRHSD17B10ALDH1A1ACHEKMT2A
SCHEMBL9160160 0.83 TSHR (0.67) TSHRHSD17B10ALDH1A1ACHEKMT2A
SCHEMBL10517583 0.82 ALDH1A1 (0.72) TSHRHSD17B10ALDH1A1CYP3A4LMNA
SCHEMBL1773527 0.81 TSHR (0.65) TSHRHSD17B10ALDH1A1ACHEKMT2A
SCHEMBL439436 0.81 TSHR (0.65) TSHRHSD17B10ALDH1A1ACHEKMT2A
Diethyl Phthalate SCHEMBL5306972 0.81 TSHR (1.00) TSHRHSD17B10ALDH1A1KMT2ACDC25B
Diethyl Phthalate SCHEMBL29404255 0.81 TSHR (1.00) TSHRHSD17B10ALDH1A1KMT2ACDC25B
Diethyl Phthalate SCHEMBL22296 0.81 TSHR (1.00) TSHRHSD17B10ALDH1A1KMT2ACDC25B
Diethyl Phthalate SCHEMBL8577506 0.79 TSHR (0.95) TSHRHSD17B10ALDH1A1KMT2ACDC25B
Diethyl Phthalate SCHEMBL7520316 0.79 TSHR (0.95) TSHRHSD17B10ALDH1A1KMT2ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5518846-A DISAZOACETYLENIC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-05-21 US disclosed
EP-0399403-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1995-04-26 EP disclosed
EP-0287073-B1 Method for processing a silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1995-03-08 EP disclosed
US-5106712-A Sensitivity, durability FUJI PHOTO FILM CO., LTD. (JP) 1992-04-21 US disclosed
US-5073465-A High sensitivity and durability FUJI PHOTO FILM CO., LTD. (JP) 1991-12-17 US disclosed
US-5053302-A Photosensitivity, durability FUJI PHOTO FILM CO., LTD. (JP) 1991-10-01 US disclosed
EP-0399403-A1 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-11-28 EP disclosed
US-4952488-A DESILVERING ACCELERATOR, ARYLUREIDO AND CARBOXAMIDO SUBSTITUTED PHENOLIC CYAN COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1990-08-28 US disclosed
US-H789-H DESILVERING USING FERRIC COMPLEX SALT FUJI PHOTO FILM CO., LTD. (JP) 1990-06-05 US disclosed
US-4865959-A HIGH SPEED COLORED IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1989-09-12 US disclosed
US-4857442-A Method for the processing of silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-08-15 US disclosed
EP-0287073-A2 Method for processing a silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-10-19 EP disclosed