SCHEMBL8995871

SCHEMBL8995871

Oc1ccc2cn[nH]c2c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
NOS1 P29475 3/20 0.44
FGFR1 P11362 4/20 0.42
FGFR2 P21802 2/20 0.42
PLK4 O00444 1/20 0.42
CHEK1 O14757 1/20 0.42
AURKA O14965 1/20 0.42
DAPK3 O43293 1/20 0.42
MAP4K4 O95819 1/20 0.42
CSF1R P07333 1/20 0.42
RET P07949 1/20 0.42
PDGFRA P16234 1/20 0.42
LTK P29376 1/20 0.42
KDR P35968 1/20 0.42
MAP2K2 P36507 1/20 0.42
FLT3 P36888 1/20 0.42
CSNK1A1 P48729 1/20 0.42
PRKX P51817 1/20 0.42
CDK5 Q00535 1/20 0.42
MAP2K1 Q02750 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2273144 0.79 NOS1 (0.50) MAPTNOS1FGFR1FGFR2PLK4
SCHEMBL2271171 0.79 MAPT (0.61) MAPTNOS1FGFR1FGFR2PLK4
SCHEMBL30675724 0.79 MAPT (0.43) MAPTNOS1FGFR1FGFR2PLK4
SCHEMBL2269592 0.79 NOS1 (0.50) MAPTNOS1FGFR1FGFR2PLK4
SCHEMBL2268804 0.79 MAPT (0.61) MAPTNOS1FGFR1FGFR2PLK4
SCHEMBL24317749 0.79 MAPT (0.43) MAPTNOS1FGFR1FGFR2PLK4
SCHEMBL11732664 0.75 FGFR1 (0.40) MAPTNOS1FGFR1FGFR2PLK4
SCHEMBL16931393 0.75 ERN1 (0.47) MAPTNOS1FGFR1FGFR2PLK4
SCHEMBL3069352 0.75 FGFR1 (0.40) MAPTNOS1FGFR1FGFR2PLK4
SCHEMBL276869 0.74 NOS1 (0.59) MAPTNOS1FGFR1PLK4CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5518846-A DISAZOACETYLENIC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-05-21 US disclosed
EP-0391399-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1995-11-02 EP disclosed
EP-0399403-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1995-04-26 EP disclosed
US-5106712-A Sensitivity, durability FUJI PHOTO FILM CO., LTD. (JP) 1992-04-21 US disclosed
US-5073465-A High sensitivity and durability FUJI PHOTO FILM CO., LTD. (JP) 1991-12-17 US disclosed
US-5053302-A Photosensitivity, durability FUJI PHOTO FILM CO., LTD. (JP) 1991-10-01 US disclosed
US-5019474-A Containing tetrakisazo charge generating compound; high sensitivity, durability FUJI PHOTO FILM CO., LTD. (JP) 1991-05-28 US disclosed
EP-0399403-A1 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-11-28 EP disclosed
EP-0391399-A1 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-10-10 EP disclosed
US-4004877-A Hair dye and its use CARL BREHMER & SOHN (DT) 1977-01-25 US disclosed