Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408720 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ETSHRMAPTADRB2 | |
| SCHEMBL14690195 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ETSHRMAPTADRB2 | |
| SCHEMBL13328208 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4ETSHRMAPTADRB2 | |
| SCHEMBL15110945 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4ETSHRMAPTADRB2 | |
| SCHEMBL2838593 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4ETSHRMAPTADRB2 | |
| SCHEMBL14883561 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL17797889 | 0.79 | ALDH1A1 (0.62) | SMN1; SMN2KDM4ETSHRMAPTADRB2 | |
| Iodide SCHEMBL14876679 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL16353031 | 0.79 | APOBEC3A (0.55) | SMN1; SMN2APOBEC3AAPOBEC3GTSHRCHRM2 | |
| SCHEMBL277670 | 0.78 | NPC1 (0.56) | SMN1; SMN2KDM4EMAPTCYP2C9ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572986-B1 | Assay for serum cholinesterase | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0572986-A1 | Assay for serum cholinesterase | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1993-12-08 | — | — | EP | disclosed |