Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.52 |
| ▸ | KDM1A | O60341 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648399 | 0.86 | L3MBTL1 (0.51) | L3MBTL1TDP1 | |
| SCHEMBL1766179 | 0.86 | MAPT (0.56) | HTR1AADRA1DADRA1AADRA1BKDM1A | |
| SCHEMBL12745447 | 0.81 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL12627780 | 0.79 | MAPT (0.50) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL15295256 | 0.79 | L3MBTL1 (0.44) | L3MBTL1TDP1 | |
| SCHEMBL10604249 | 0.78 | MAPT (0.56) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL30080427 | 0.77 | MAPT (0.58) | HTR1AKDM1AL3MBTL1MAPTMAPK1 | |
| SCHEMBL9706382 | 0.77 | MAPT (0.58) | HTR1AKDM1AL3MBTL1MAPTMAPK1 | |
| SCHEMBL29000550 | 0.77 | HTR1A (0.57) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL12745444 | 0.76 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537742-B1 | Styrene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5514711-A | ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0537742-A2 | Styrene derivatives | Mitsubishi Chemical Corporation (JP) | 1993-04-21 | — | — | EP | disclosed |