Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996000 | 0.87 | HPGD (0.46) | NPC1HPGDTP53ALDH1A1RAB9A | |
| SCHEMBL5685094 | 0.81 | NPC1 (0.50) | NPC1HPGDLMNATP53ALDH1A1 | |
| Iodide SCHEMBL8700644 | 0.81 | CTSD (0.45) | CTSDNPC1HPGDLMNATP53 | |
| SCHEMBL10339057 | 0.80 | HPGD (0.44) | NPC1HPGDLMNACA12CA1 | |
| Iodide SCHEMBL8995953 | 0.80 | TP53 (0.49) | NPC1HPGDLMNATP53ALDH1A1 | |
| SCHEMBL4624134 | 0.79 | SLC6A2 (0.42) | NPC1HPGDRAB9AHTTKMT2A | |
| SCHEMBL8441866 | 0.78 | CTSD (0.55) | CTSDNPC1HPGDSTAT3ALDH1A1 | |
| SCHEMBL31257134 | 0.74 | CTSD (0.55) | CTSDNPC1HPGDSTAT3ALDH1A1 | |
| SCHEMBL4303504 | 0.74 | CTSD (0.55) | CTSDNPC1HPGDSTAT3ALDH1A1 | |
| SCHEMBL31318924 | 0.74 | CTSD (0.55) | CTSDNPC1HPGDSTAT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063021-B1 | METHOD FOR DETERMINING THE ACTIVITY OF CHOLINESTERASES AND DIAGNOSTIOC SOLUTION FOR USE THEREIN | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1984-10-31 | — | — | EP | claimed |
| JP-57167000-A | — | — | None | — | — | JP | disclosed |
| EP-0572986-B1 | Assay for serum cholinesterase | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0572986-A1 | Assay for serum cholinesterase | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1993-12-08 | — | — | EP | disclosed |
| JP-S57167000-A | DETERMINATION OF CHOLINESTERASE ACTIVITY | FUJIREBIO INC | 1982-10-14 | — | — | JP | disclosed |